Oral platelet glycoprotein IIb/IIIa receptor inhibitors-part II
نویسندگان
چکیده
منابع مشابه
Platelet Glycoprotein IIb/IIIa Inhibitors
Glycoprotein IIb/IIIa (GPIIb-IIIa) complexes (integrin aIIbb3) mediate platelet aggregation by binding fibrinogen or von Willebrand factor (vWF), protein cofactors that form bridges between adjacent platelets. The cross-linked adhesive proteins assemble platelets into the aggregate. Agents that block the function of the GPIIb-IIIa complex of platelets constitute a powerful new generation of ant...
متن کاملPlatelet glycoprotein IIb/IIIa inhibitors.
To the Editor: Platelet glycoprotein (GP) IIb/IIIa antagonists only prompt an overall 8.5% relative reduction in 30-day deaths or myocardial infarction in acute coronary syndromes (ACS),1 and Quinn et al1 suggested that this limited benefit may be due to factors such as antagonist-induced platelet activation. I suggest that limited benefits of GP IIb/IIIa inhibition are due basically to limited...
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BACKGROUND Medical decision making must often be performed despite incomplete evidence. An example is the choice of a glycoprotein IIb/IIIa (GP2b3a) inhibitor, a class of potent antiplatelet medications, as adjunctive therapy during percutaneous coronary interventions (PCIs). GP2b3a inhibitor efficacy in reducing adverse outcomes has been well documented with multiple placebo-controlled randomi...
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Evaluation of: Sanchez, P, Gimeno F, Ancillo P et al.: Role of the paclitaxel-eluting stent and tirofiban in patients with ST elevation myocardial infarction undergoing postfibrinolysis angioplasty (GRACIA 3 Trial). Circ. Cardiovasc. Interv. 3, 297–307 (2010). In ST elevation myocardial infarction patients presenting to nonpercutaneous coronary intervention (PCI)-capable hospitals, a pharmacoin...
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Squamous cell carcinoma and its histologic variants account for over 90% of all malignancies of the oral cavity. Early squamous cell carcinoma often presents as a white lesion (leukoplakia), red lesion (erythroplakia), or a combination of both (erythroleukoplakia). 1,2,3,4 However, with time, superficial ulceration of the mucosal surface may develop. As the lesion grows, it may become an exophy...
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ژورنال
عنوان ژورنال: Clinical Cardiology
سال: 2003
ISSN: 0160-9289,1932-8737
DOI: 10.1002/clc.4960260903